Corticosteroids are used most often for MESI, but carry significant safety risks and efficacy can be limited Most frequently prescribed medications in patients with macular edema due to noninfectious uveitis, across any line of therapy 1 • Steroids were the most common medication class and remain the standard of care 1 • XIPERE ® (suprachoroidal triamcinolone acetonide) is the only approved local ocular treatment in the U.S. • Approximately 30-40% of patients do not fully respond to intraocular steroids 2,3 • Intraocular steroids are avoided in the pediatric population and used with caution in adults due to high risk of permanent glaucoma damage and cataract formation 1. Eichenbaum, D. et al. ARVO 2025 Poster Presentation 643. 2. Teper SJ. Journal of Clinical Medicine. 2021; 10(18):4133. 3. Tomkins-Netzer O et al. Ophthalmology. 2015. 122:2351-2359. 73.3% Steroids 49