Zenkuda in wAMD: The ongoing Phase 3 DAYBREAK study is designed to evaluate immediacy and real-world durability Topline data Sept. 2026 Noninferiority Phase 3 DAYBREAK Objective: Assess immediacy + durability potential in wAMD 38 6-month durability potential AI-based tool precisely measures fluid in the eye to optimize treatment per patient at each individualized treatment visit (after loading doses) High-need patients Treats until dry, enables monthly dosing and detects disease reactivation earlier Long-durability patients Allows patients without active disease to safely go to every 6-month dosing Primary Endpoint End of Study

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