86 Kodiak Sciences Inc. Consolidated Statements of Stockholders’ Equity (in thousands, except share and per share amounts) Common Stock Additional Paid-In Accumulated Other Comprehensive Accumulated Total Stockholders’ Shares Amount Capital Income (Loss) Deficit Equity Balances at December 31, 2019 ........... 44,413,404 $ 5 $ 503,475 $ 10 $ (158,131) $ 345,359 Issuance of common stock upon exercise of stock options............. 704,675 — 6,248 — — 6,248 Issuance of common stock in connection with follow-on offering, net of offering costs of $32,984............................. 5,972,222 — 612,016 — — 612,016 Issuance of common stock upon vesting of restricted stock units, net of taxes withheld ................. 22,001 — (487) — — (487) Stock-based compensation expense................................ — — 30,668 — — 30,668 Other comprehensive income.......... — — — 43 — 43 Net loss.................................. — — — — (133,096) (133,096) Balances at December 31, 2020 ........... 51,112,302 5 1,151,920 53 (291,227) 860,751 Issuance of common stock upon exercise of stock options............. 463,796 — 7,743 — — 7,743 Issuance of common stock upon vesting of restricted stock units ................................... 93,218 — — — — — Issuance of common stock pursuant to employee stock purchase plan ......................... 6,958 — 484 — — 484 Issuance of common stock upon exercise of common stock warrants ............................... 149,983 — — — — — Stock-based compensation expense................................ — — 61,385 — — 61,385 Other comprehensive loss.............. — — — (53) — (53) Net loss.................................. — — — — (266,990) (266,990) Balances at December 31, 2021 ........... 51,826,257 5 1,221,532 — (558,217) 663,320 Issuance of common stock upon exercise of stock options............. 126,999 — 1,770 — — 1,770 Issuance of common stock upon vesting of restricted stock units ................................... 103,032 — — — — — Issuance of common stock pursuant to employee stock purchase plan ......................... 27,863 — 174 — — 174 Issuance of common stock upon exercise of common stock warrants ............................... 249,699 — — — — — Stock-based compensation expense................................ — — 106,033 — — 106,033 Other comprehensive loss.............. — — — (1,307) — (1,307) Net loss.................................. — — — — (333,823) (333,823) Balances at December 31, 2022 ........... 52,333,850 $ 5 $ 1,329,509 $ (1,307) $ (892,040) $ 436,167 The accompanying notes are an integral part of these consolidated financial statements.