Macular edema is the leading cause of vision loss among patients with ocular inflammation Normal Retina on OCT Macular edema on OCT Fluid that leaked into the retina causing macular edema 1. Br J Ophthalmol. 2004;88(9):1159-1162. 2. Tomkins-Netzer O, et al. Ophthalmology. 2021 May;128(5):719-728. 35 • Noninfectious MESI represents a set of serious ocular inflammatory conditions that cause significant vision loss. • Ocular inflammation is the 4 th leading cause of vision loss among working aged adults in the developed world 1 • Approximately 1/3 of patients with ocular inflammation develop macular edema in the U.S. 2 • Symptoms at diagnosis typically include distorted central vision, vitreous floaters, reduced visual acuity, and decreased color and contrast sensitivity • MESI leads to photoreceptor damage and can result in permanent loss of visual acuity