Tarcocimab and KSI-501 bring the best of both worlds – with a science of high immediacy and high durability at the same time in a single biologic Increasing molecular size (kDa) 149 kDa 210 kDa 950 kDa 1000 kDa 149 kDa Immediacy is achieved with lower molecular weight intravitreal biologics Durability increases as molecular weight increases for intravitreal biologics 17