82 Kodiak Sciences Inc. Consolidated Statements of Stockholders’ Equity (in thousands, except share and per share amounts) Common Stock Additional Paid-In Accumulated Other Comprehensive Accumulated Total Stockholders’ Shares Amount Capital Income (Loss) Deficit Equity ................................. Balances at December 31, 2022 52,333,850 $ 5 $ 1,329,509 $ (1,307) $ (892,040) $ 436,167 ....................................... Exercise of stock options 7,528 — 60 — — 60 .................................. Restricted stock units vested 116,403 — — — — — ............................................. Proceeds from ESPP 50,821 — 182 — — 182 ..................................... Stock-based compensation — — 88,556 — — 88,556 ................................. Other comprehensive income — — — 1,307 — 1,307 ............................................................... Net loss — — — — (260,491) (260,491) ................................. Balances at December 31, 2023 52,508,602 5 1,418,307 — (1,152,531) 265,781 ....................................... Exercise of stock options 82,790 — 394 — — 394 .................................. Restricted stock units vested 86,559 — — — — — ............................................. Proceeds from ESPP 48,965 — 107 — — 107 ..................................... Stock-based compensation — — 60,213 — — 60,213 ............................................................... Net loss — — — — (176,207) (176,207) ................................. Balances at December 31, 2024 52,726,916 5 1,479,021 — (1,328,738) 150,288 ....................................... Exercise of stock options 925,813 — 5,363 — — 5,363 . Proceeds from public offering, net of offering costs 8,000,000 1 172,655 — — 172,656 .................................. Restricted stock units vested 45,190 — — — — — ............................................. Proceeds from ESPP 60,535 — 180 — — 180 ..................................... Stock-based compensation — — 58,863 — — 58,863 ............................................................... Net loss — — — — (229,967) (229,967) ................................. Balances at December 31, 2025 61,758,454 $ 6 $ 1,716,082 $ — $ (1,558,705) $ 157,383 See notes to consolidated financial statements.

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