Toward unified MESI management: can KSI-101 deliver potency without the glaucoma and surgical burden of steroids? • Idiopathic • Vogt-Koyanagi-Harada disease • Behcet's disease • HLA-B27 associated • Juvenile idiopathic arthritis • Multiple sclerosis • Pars planitis • Birdshot chorioretinopathy • Multifocal choroiditis • Sarcoidosis • Refractory Irvine Gass syndrome Complex Diagnosis Considerations in Steroid Selection • Glaucoma history, steroids intraocular pressure response • Phakic versus pseudophakic • Location of the primary inflammation • Unilateral versus bilateral • Prior response/fellow eye response • Inflammation active versus inactive • Chronicity of the MESI • Vision • Age Complex Treatment Decisions Treat with intravitreal biologic KSI-101 Simplified Diagnosis and Treatment Journey Diagnosis MESI with OCT Today 108 Patients are not undertreated due to side effects of steroid use Patients can achieve disease remission and/or chronic disease control