APEX KSI-101 in DME – Baseline Characteristics KSI-101 2.5 mg (n=4) KSI-101 5 mg (n=4) KSI-101 10 mg (n=4) All KSI-101 (N=12) Age, years, mean (SD) 54.5 (10.6) 68.3 (5.74) 56.5 (4.7) 59.8 (9.3) Female, n (%) 0 0 2 (50) 2 (16.7) Race, White, n (%) 4 (100) 4 (100) 4 (100) 12 (100) DME disease duration, months , mean (SD) 1.8 (1.6) 13.0 (22.0) 4.1 (3.1) 6.3 (12.7) BCVA, ETDRS Letters , mean (SD) 69.8 (3.3) 58.0 (13.9) 63.8 (9.9) 63.8 (10.4) Snellen equivalent ~20/40 ~20/63 ~20/50 ~20/50 OCT CST, μm , mean (SD) 442.0 (45.4) 483.0 (54.3) 485.8 (83.8) 470.3 (61.0) Lens Status, pseudophakic, n (%) 1 (25) 1 (25) 1 (25) 3 (25) 67 Preliminary results. As the APEX study is ongoing, final results may be different due to additional data collection or data cleaning. Includes all patients randomized. SD= standard deviation; BCVA= best corrected visual acuity; OCT= optical coherence tomography; CST= central subfield thickness