Tarcocimab demonstrated consistent 20-day ocular half-life across wet AMD, DME and RVO patients All Wet AMD DME RVO 0 10 20 30 40 50 n=47 n=23 DME n=8 n=16 Tarcocimab Human Ocular Half-Life by Indication RVO n=16 wAMD n=23 All n=47 Height of the box represents the mean; error bars represent standard deviation. Aqueous Humor t 1/2 (days) 26