3 6 Macular edema, the common clinical presentation of a wide spectrum of diseases, can be caused by inflammation and/or by VEGF over-expression Inflammation driven VEGF driven Uveitis Systemic or Autoimmune Disease Inflammatory CNV Post Surgical Diabetic Macular Edema Retinal Vein Occlusion Neovascular AMD Myopic CNV AMD: age-related macular degeneration; CNV: choroidal neovascularization Macular Edema Spectrum of Diseases Macular edema secondary to inflammation Retinal vascular and degenerative diseases