KSI-101 achieves dryness and normalizes the retinal architecture in the majority of patients 1 2 3 4 5 6 7 8 9 10 12 11 13 KSI-101 2.5 mg 14 15 16 17 18 19 20 21 22 24 23 25 26 KSI-101 5 mg 27 28 29 30 31 32 33 34 35 36 37 38 39 KSI-101 10 mg Week 12 visit shown above. Subject ET at W12. No data available for W16 or W24 Subject Day 1 Week 16 Week 24 12 weeks since last injection Post-loading Subject Day 1 Week 16 Week 24 12 weeks since last injection Post-loading Subject Day 1 Week 16 Week 24 12 weeks since last injection Post-loading Reactivation at W20 Received rescue therapy (W24 data censored) 12