86 Kodiak Sciences Inc. Consolidated Statements of Operations and Comprehensive Loss (in thousands, except share and per share amounts) Year Ended December 31, 2024 2023 2022 Operating expenses Research and development ......................................................................... $ 126,095 $ 206,298 $ 267,591 General and administrative ......................................................................... 60,754 71,023 73,788 Total operating expenses ........................................................................ 186,849 277,321 341,379 Loss from operations...................................................................................... (186,849) (277,321) (341,379) Interest income.......................................................................................... 11,148 16,733 7,071 Interest expense......................................................................................... — (13) (18) Other income (expense), net ....................................................................... (506) 110 503 Net loss ........................................................................................................ $ (176,207) $ (260,491) $ (333,823) Net loss per common share, basic and diluted................................................... $ (3.35) $ (4.97) $ (6.39) Weighted-average shares of common stock outstanding used in computing net loss per common share, basic and diluted............................. 52,583,148 52,414,256 52,249,620 Other comprehensive income (loss) Change in unrealized gains (losses) related to available-for-sale debt securities, net of tax ......................................................................... — 1,307 (1,307) Total other comprehensive income (loss) ................................................. — 1,307 (1,307) Comprehensive loss....................................................................................... $ (176,207) $ (259,184) $ (335,130) The accompanying notes are an integral part of these consolidated financial statements.