iii • future agreements with third parties in connection with the commercialization of our product candidates; • the size and growth potential of the markets for our product candidates, if approved for commercial use, and our ability to serve those markets; • existing regulations and regulatory r developments in the United States and foreign countries; • the expected potential benefits of strategic collabor a ation agreements and our ability to attract collabor a ators with development, regulatory r and commercialization expertise; • the scope of protection we are able to establ a ish and maintain for intellectua t l property rights covering our product candidates and technology; • potential claims relating to our intellectua t l property and third-party intellectua t l property; • our ability to contract with third-party suppl u iers and manufac f turers and their ability to perform adequately; • the pricing and reimbursement of our product candidates, if approved; • the impact of the unfav f orable U.S. and global economic conditions on our business and operations, the business and operations of our collabor a ators, and on the global economy; • our aspirational goals and objectives related to our human capital resources and workforce objectives; • our ability to attract and retain key managerial, scientific f and medical personnel; • the accuracy of our estimates regarding the suffic f iency of our cash resources, expenses, future revenue, capi a tal requirements and needs for additional financing; and • our financial performance. All forward-looking statements are based on information availabl a e to us on the date of this Annual Report on Form 10- K and we will not update any of the forward-looking statements afte f r the date of this Annual Report on Form 10-K, except as required by law. Our actua t l results could differ materially from those discussed in this Annual Report on Form 10-K. The forward-looking statements contained in this Annual Report on Form 10-K, and other written and oral forward-looking statements made by us from time to time, are subj u ect to certain risks and uncertainties that could cause actua t l results to differ materially from those anticipated in the forward-looking statements, and you should not regard these statements as a representation or warranty by us or any other person that we will achieve our objectives and plans in any specified time frame, or at all. Factors that might cause such a difference include, but are not limited to, those discussed in the following discussion and within Part I, Item 1A “Risk Factors” of this Annual Report on Form 10-K. In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subj u ect. These statements are based upon information availabl a e to us as of the date of this Annual Report on Form 10-K, and although we believe such information forms a reasonabl a e basis for such statements, such information may be limited or incomplete, and our statements should not be read to indicate that we have conducted a thorough inquiry into, or review of,f all potentially availabl a e relevant information. These statements are inherently uncertain and investors are cautioned not to unduly rely upon these statements. All brand names or trademarks k appearing in this Annual Repor e t on Form 10-K are the propertyt of their respective holders. Unless the context requires otherwise, refe e rences in this Annual Repor e t on Form 10-K to “Kodi K ak” the “Com C pany m ,” y “we,” “us,” and “our” refe e r to Kodiak Sciences Inc. and itst subsidiaries.